::: 淡江大學 　

LOGO
::: | 回首頁 　
 網站位置：首頁 > 師資陣容 >李長欣

:::

李長欣（Chang-Shin Lee）

物理化學、結構生物學、生醫核磁共振
Physical Chemistry, Structure Biology, Biomedicine NMR

淡江大學化學系助理教授（2003~迄今）
中央研究院生化所博士後研究員（1997-1999）
清華大學化學系博士（1997）
淡江大學化學系學士（1982-1986）

Tamkang University , Assistant Professor
Academia Sinica, Postdoctoral Research Fellow
National Tsing Hua University , Ph.D.
Tamkang University , B.S.

李長欣

教師歷程系統

研究方向

  1. 生醫核磁共振
  2. 物理化學
  3. 結構生物學

研究興趣

  1. 利用核磁共振方法研究生物分子之結構，包括生物分子之溶液結構、動態行為、ligand-receptor作用的影響等。
  2. 以高解析固態MAS方法，進行 ex vivo 細胞疾病之生理代謝研究。

Our researches focus on :
By using NMR methods to investigate biomolecular structures including solution structure, molecular dynamics and ligand-receptor binding.

By using ex vivo HRMAS to investigate correlation of cellular biochemical changes and different pathologies.

 

 

 

E-mail: cshlee@mail.tku.edu.tw

代表性著作

  1. Teng-Yi Huang, Hsiao-Wen Chung, Ming-Yen Chen, Lung-Hui Giiang, Shy-Chyi Chin, Chang-Shin Lee, Cheng-Yu Chen, Yi-Jui Liu. Quantification of supratentorial CSF production rate in healthy adults: A high temporal and spatial resolution 2D cine phase-contrast MRI study. Radiology 2004; 233(2):603-8
     
  2. Wen-Chau Wu, Chao-Ching Huang, Hsiao-Wen Chung, Michelle Liou, Chun-Jen Hsueh, Chang-Shin Lee, Ming-Long Wu, Cheng-Yu Chen. Hippocampal Alterations in Children with Temporal Lobe Epilepsy with or without a History of Febrile Convulsions: Evaluations with MR Volumetry and Proton MR Spectroscopy. AJNR Am J Neuroradiol. 2005 May;26(5):1270-5.
     
  3. Yi-Fang Tu, Cheng-Yu Chen, Chao-Ching Huang, Chang-Shin Lee. Vacuolating megalencephalic leukoencephalopathy with mild clinical course validated by diffusion tensor imaging and MR spectroscopy. AJNR Am J Neuroradiol. 2004 Jun-Jul;25(6):1041-5.
     
  4. Yi-Jui Liu, Cheng-Yu Chen, Hsiao-Wen Chung, Ing-Jye Huang, Chang-Shin Lee, Shy-Chyi Chin, Michelle Liou. Temporal evolution of neuronal necrosis following ischemic injury in the middle cerebral artery territory: deep watershed versus territorial infarct subtypes on MR perfusion and spectroscopic imagings. Radiology. 2003;229:366-374
     
  5. Yi-Jui Liu, Hsiao-Wen Chung, Ing-Jye Huang, Fu-Nien Wang, Shy-Chyi Chin, Chang-Shin Lee, Cheng-Yu Chen. J. Neuroimaging, 2002;12:330-338.
     
  6. Lee, W. T., Lee, C. S., Pan, Y. L. and Chang C. “Temporal Changes of Cerebral Metabolites and Striatal Lesions in Acute 3-Nitropropionic Acid Intoxication in the Rat”Magn. Res. Med. 2000, 44, 29-34.
     
  7. Lee, C. S., Kumar, T. K. S., Cheng, J. W., Yu, C. Main-Chain Internal Dynamics of Cardiotoxin II from Taiwan Cobra as Studied by Carbon-13 NMR at Natural Abundance: Delineation of the role of functionally important residues,” Biochemistry 1998, 37,