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潘伯申(Po-Shen Pan)

藥物分子設計、合成與生物活性之評估


學歷

加州大學聖地牙哥分校暨加州州立大學聖地牙哥分校化學博士 (2008, 06)

交通大學應化所碩士 (2000, 06)

輔仁大學化學系學士 (1998, 06)

 

經歷

淡江大學化學系專任助理教授 (2010, 08 to present)

美國賓州大學化學系博士後研究員 (2008, 10 to 2010, 08)

工業技術研究院副研究員 (2000, 08 to 2002, 05)

Education

Ph.D. in Chemistry, UCSD and SDSU (2008, 06)

M.S. in Chemistry, National Chiao-Tung University (2000, 06)

B.S. in Chemistry, Fu-Jen University (1998, 06)

Experience

Assistant Professor, Tamkang University (2010, 08 to present)

Postdoctoral Fellow, University of Pennsylvania (2008, 10 to 2010, 08)

Associate Researcher, Industrial Technology Research Institute (2000, 08 to 2002, 05)


潘伯申

Office: 02-2621-5656 轉 2842

Email: popan@mail.tku.edu.tw

實驗室網頁:
http://psplabfamily.weebly.com/ 

 

 

2010實驗室合照

Honors and Awards

1. CSUPERB travel grant San Diego, CA 2006

2. CSUPERB travel grant San Diego, CA 2005

3. Harry E. Hamber Memorial Scholarship San Diego, CA 2004

4. Don Eden Graduate Student Research Award San Diego, CA 2004

 

1. Gary A. Molander*, Livia N. Cavalcanti, Belgin Canturk, Po-Shen Pan, Lauren E. Kennedy, “Efficient Hydrolysis of Organotrifluoroborates via Silica Gel and Water”, Journal of Organic Chemistry, 2009, v74, p7364-7369

2.   Po-Shen Pan, Robert C. Vasko, Stephanie Lapera, Victoria A. Johnson, Robert P. Sellers, Chun-Chieh Lin, Chung-Mao Pan, Melinda R. Davis, Veronica C. Ardi, and Shelli R. McAlpine* "A Comprehensive Study of Sansalvamide A Derivatives: the Structure-Activity Relationships of 78 derivatives in two pancreatic cancer cell lines", Bio. Org. Med. Chem. 2009, v17, p5806-5825

3.   Rodrigo Rodriguez, Chung-Mao Pan, William Disman, Po-Shen Pan, Robert C. Vasko, and Shelli R. McAlpine* "Structure-Activity of Sansalvamide A Derivatives and Their Mechanism of Action in Pancreatic Cancer Cell Line PL45", J. Mex. Chem. Soc., 2008, v52, p201-211

4.   Erinprit K. Singh, Suchitra Ravula, Chung-Mao Pan, Po-Shen Pan, Robert C. Vasko, Stephanie Lapera, Sujith, Mary Kay Pflum and Shelli R. McAlpine* "Synthesis and Biological Evaluation of Histone Deactylase Inhibitors that are Based on the FR235222 Scaffold", Bio. Org. Med. Chem. Lett, 2008, v18, p2549-2554

5.   Melinda R. Davis, Thomas J. Styers, Rodrigo A. Rodriguez, Po-Shen Pan, Robert C. Vasko, and Shelli R. McAlpine* "Synthesis and Cytotoxicity of a New Class of Potent Decapeptides macrocycles", Org Lett., 2008, v10, p177-180

6.   Po-Shen Pan, Kathleen L. McGuire, and Shelli R. McAlpine* "Identification of Compounds Potent Against Pancreatic Cancer Cell Lines", Bio. Org. Med. Chem. Lett., 2007,  v17, p5072-5077

7.   Rodrigo Rodriguez, Po-Shen Pan, Chung-Mao Pan, Suchitra Ravula, Stephanie Lapera, Erin Singh, Thomas J. Styers, Joseph D. Brown, Julia Cajica, Emily Parry, Katerina Otrubova, and Shelli R. McAlpine* "Synthesis of Second Generation Sansalvamide A Derivatives: Novel Templates as Potent Anti-tumor Agents", J. Org. Chem., 2007, v72, p1980-2002

8. Thomas J. Styers, Ahmet Kekec, Rodrigo A. Rodriguez, Joeseph D. Brown, Julia Cajica, Po-Shen Pan, Emily Parry, Irene Medina, Ricardo Corral, Stephanie A. Lapera, Katerina Otrubova, Chung-Mao Pan, Kathleen L. McGuire, Shelli R. McAlpine*, “Synthesis of Sansalvamide A Derivatives and Their Cytotoxicity in the MSS Colon Cancer Cell Line HT-29” Bioorganic and Medicinal Chemistry, 2006, v14, p5625-5631

9.   Po-Shen Pan, Fiona A. Curtis, Chris L. Carroll, Irene Medina, Lisa A. Liotta, Gary J. Sharples, and Shelli R. McAlpine*, “Novel Antibiotics: C-2 Symmetrical Macrocycles Affecting Holliday Junction DNA processing” Bioorganic and Medicinal Chemistry, 2006, v14, p4731-4739

10.   Katerina Otrubova, Thomas J. Styers, Po-Shen Pan, Rodrigo Rodriguez, Kathleen L. McGuire,* and Shelli R. McAlpine*, “Synthesis and Novel Structure-Activity Relationships of Potent  Sansalvamide A Derivatives” Chemical Communications, 2006, p1033-1034

11.   Thomas J. Styers, Rodrigo Rodriguez, Po-Shen Pan, and Shelli R. McAlpine*, “Synthesis of Novel Sansalvamide A Derivatives via New, High Yielding Macrocyclization Conditions” Tetrahedron Letters, 2006, v47, p515-517

12. Chris L. Carroll. C, Jennifer V. C. Johnston, Ahmet Kekec, Joeseph D. Brown, Emily Parry, Junlia Cajica, Irene Medina, Kristina M. Cook, Ricardo Corral, Po-Shen Pan; Shelli R. McAlpine*, “Synthesis and Cytotoxicity of Novel Sansalvamide A Derivatives” Organic Letters, , 2005, v7, p3481-3484

13. Lisa A. Liotta, Irene Medina, Jennifer L. Robinson, Chris L. Carroll, Po-Shen Pan, Ricardo Corral, Jennifer V. C. Johnston, Kristina M. Cook, Fiona A. Curtis, Gary J. Sharples, Shelli R. McAlpine*, “Novel Antibiotics: Second Generation Macrocyclic Peptides Designed to Trap Holliday Junctions” Tetrahedron Letters, 2004, v45, p8447-8450